PREVALENCE OF THE BRCA1 FOUNDER MUTATION C.5266DUPIN BRAZILIAN INDIVIDUALS AT-RISK FOR THE HEREDITARY BREAST AND OVARIAN CANCER SYNDROME

Prevalence of the BRCA1 founder mutation c.5266dupin Brazilian individuals at-risk for the hereditary breast and ovarian cancer syndrome

Abstract About 5-10% of breast and ovarian carcinomas are hereditary and most of these result from germline mutations in the BRCA1 and BRCA2 genes.In women of Ashkenazi Jewish ascendance, up to 30% of breast and ovarian carcinomas may Harnesses be attributable to mutations in these genes, where 3 founder mutations, c.68_69del (185delAG) and c.5266d

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Effect of Cu/Ni foil interlayer on microstructure and mechanical properties of laser welded aluminum/steel joints

Laser welding of aluminum/steel dissimilar metals with Ni and Ni/Cu foils as intermediate layers was studied in this paper.The effect of Cu/Ni foil on microstructure and properties of dissimilar laser welded aluminum/steel joints was systematically investigated.Scanning electron microscope (SEM) and its own energy dispersive spectrometer (EDS) were

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The Cardamine enshiensis genome reveals whole genome duplication and insight into selenium hyperaccumulation and tolerance

Abstract Cardamine enshiensis is a well-known selenium (Se)-hyperaccumulating plant.Se is an essential trace element associated with many health benefits.Despite its critical importance, genomic information of this species is limited.Here, we report a chromosome-level genome assembly of C.enshiensis, which consists of 443.4 Mb in 16 chromosomes wit

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